Searchable abstracts of presentations at key conferences in endocrinology

ea0029p711 | Diabetes | ICEECE2012

Rapidly and strong suppression of human acylated ghrelin serum concentrations during infusion of des-acyl ghrelin in obese diabetic subjects.

Ozcan B. , Neggers S. , Reifel Miller A. , Yang H. , Delhanty P. , Allas S. , Abribat T. , van der Lelij A.

Aim: To assess the effects of a continuous overnight infusion of two doses of UAG (3&10 μg UAG/kg.hr-1) versus placebo in a double blind cross-over study on AG levels, as well on glucose and insulin response to a standard breakfast meal (SBM) in 8 overweight patients with type 2 diabetes (HbA1c 6.5-7.5%).Methods: During these 3 admissions, in randomized order, all subjects received either placebo, or UAG 3 μg/kg.hr-1 or UAG 10 μg/kg.hr...